Papers/Technical Information

Papers

PapersReference ducuments using the beads that compound was immobilized

R. Kamihira et al. (2022)

Preparation and Application of a Chemical Probe for Identifying the Targets of the Marine Cyclic Peptide Kapakahine A
Molecules 2022, 27, 1072

Target Products / Applications

Alkyne beads Chemical Biology

PapersReference ducuments using the beads that compound was immobilized

K. Kobayashi-Nakamura et al. (2022)

Rhamnazin suppresses melanosome transport by promoting the ubiquitin-mediated proteasomal degradation of melanophilin
Journal of Dermatological Science 105 (2022) 45–54

Target Products / Applications

Epoxy beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Hirata et al.(2022)

Sirtuin inhibition and neurite outgrowth effect as new biological activities for Areca catechu nut alkaloids
Phytomedicine Plus 2 (2022) 100294

Target Products / Applications

NH₂ beads Chemical Biology Compounds Immobilization

PapersOthers（Reference ducuments）Development of a fluorescent probe

Lee S Nguyen et al.(2022) nSMOL

Reversal of immune-checkpoint inhibitor fulminant myocarditis using personalized-dose-adjusted abatacept and ruxolitinib: proof of concept
J Immunother Cancer 2022;10:e004699

PapersOthers（Reference ducuments）Limited proteolysis

N. Iwamoto et al. (2022) [nSMOL]

A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics
Analyst, DOI: 10.1039/d2an01032a

Target Products / Applications

NHS beads

PapersOthers（Reference ducuments）

Oda et al.(2022)

Direct Visualization of General Anesthetic Propofol on Neurons by Stimulated Raman Scattering Microscopy
iScience 25, 103936, March 18, 2022

Target Products / Applications

Alkyne beads

PapersOthers（Reference ducuments）Immunostaining

Onishi et al.(2022) [ExoCounter]

Application of Magnetic Nanoparticles for Rapid Detection and In Situ Diagnosis in Clinical Oncology
Cancers 2022, 14, 364

Target Products / Applications

FF beads/ FS beads Virus / Exosome Isolation Antibodies Immobilization

PapersOthers（Reference ducuments）Use for measurement system

Ashiba et al.(2022)

Quick and ultra-sensitive digital assay of influenza virus using sub-picoliter microwells
Analytica Chimica Acta Volume 1213, 22 June 2022, 339926

Target Products / Applications

Virus / Exosome Isolation Compounds Immobilization

PapersOthers（Reference ducuments）Exosome

T. Anzai et al. (2022)

Identification of CD73 as the Antigen of an Antigen-Unknown Monoclonal Antibody Established by Exosome Immunization, and Its Antibody–Drug Conjugate Exerts an Antitumor Effect on Glioblastoma Cell Lines
Pharmaceuticals 2022, 15, 837

Target Products / Applications

NeutrAvidin beads Streptavidin beads Virus / Exosome Isolation

PapersOthers（Reference ducuments）Use for measurement system

Sharma et al.(2022)

Smartphone-based On-chip Homogenous Sensing by Analysis of Dynamics of Oscillating Polystyrene Particles under Dielectrophoretic Forces
Sensors and Materials, Vol. 34, No. 6 (2022) 2089–2104

Target Products / Applications

NH₂ beads

PapersOthers（Reference ducuments）

Luca Barbero et al.(2022)

Assessing Major Histocompatibility Complex Associated Peptide Proteomics assay as a tool to predict immunogenicity potential of protein therapeutics and antigens
Research Square, 19 Aug 2022

PapersOthers（Reference ducuments）

Dat Nguyen-Tien et al.(2022)

Identification of the interacting partners of a lysosomal membrane protein in living cells by BioID technique
STAR Protocols 3, 101263, June 17, 2022

Target Products / Applications

Magnet stand

PapersOthers（Reference ducuments）Limited proteolysis

N. Iwamoto et al. (2022) [nSMOL]

Structure-Indicated LC-MS/MS Bioanalysis of Therapeutic Antibodies
Methods Mol Biol. 2022;2313:187-205

Target Products / Applications

NHS beads

PapersReference ducuments using the beads that protein was immobilized

Kusakabe et al.(2022)

Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein
iScience 25, 104040, April 15, 2022

Target Products / Applications

Streptavidin beads NeutrAvidin beads Antibodies Immobilization

Papers

Matsumoto et al.(2021)

Inhibitory effects of cynaropicrin and related sesquiterpene lactones from leaves of artichoke (Cynara scolymus L.) on induction of iNOS in RAW264.7 cells and its high-affinity proteins
Journal of Natural Medicines volume 75, pages381–392 (2021)

PapersReference ducuments using the beads that compound was immobilized

Bellail et al.(2021)

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors
SCIENCE TRANSLATIONAL MEDICINE 13 Oct 2021 Vol 13, Issue 615

Target Products / Applications

Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Hamoya et al.(2021)

Artesunate inhibits intestinal tumorigenesis through inhibiting wnt signaling
Carcinogenesis, 2021, Vol. 42, No. 1, 148–158

Target Products / Applications

NH₂ beads Chemical Biology Compounds Immobilization

PapersOthers（Reference ducuments）

Ouyang et al.(2021)

Assessment of changes in genetic transcriptome in nasal epithelial cells exposed to ozone-aged black carbon and pollen allergen by high-throughput transcriptomics
Allergy Asthma Clin Immunol (2021) 17:52

PapersOthers（Reference ducuments）Use for measurement system

Y. Suzuki et al.(2021)

Development of Lectin Modified Fluorescent Magnetic Particles for Highly Sensitive Detection of Glycoconjugates
Sensors 2021, 21, 5512

Target Products / Applications

Streptavidin beads FF beads/ FS beads Proteins Immobilization

PapersReference ducuments using the beads that compound was immobilized

Ito et al.(2021)

Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology
Cell Chemical Biology 28, July 15, 2021

Target Products / Applications

NH₂ beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that protein was immobilized

Kambe et al.(2021)

Enhanced β2-microglobulin binding of a “navigator” molecule bearing a single-chain variable fragment antibody for artificial switching of metabolic processing pathways
Biomater. Sci., 2021, 9, 5551–5558

Target Products / Applications

Protein A beads Protein G beads Immunoprecipitation Antibodies Immobilization

PapersReference ducuments using the beads that DNA was immobilized

Ide et al.(2021)

Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs
Epigenetics & Chromatin (2021) 14:46

Target Products / Applications

Streptavidin beads NeutrAvidin beads Analysis of DNA / RNA Binding Substances DNA

PapersReference ducuments using the beads that compound was immobilized

Dormán et al.(2021)

Target identification and polypharmacology of nutraceuticals
Nutraceuticals (Second Edition) Efficacy, Safety and Toxicity 2021, Pages 315-343

Target Products / Applications

Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Miao-Miao Zhao et al.(2021)

Berberine is an insulin secretagogue targeting the KCNH6 potassium channel
NATURE COMMUNICATIONS(2021) 12:5616

Target Products / Applications

Epoxy beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Watanabe et al.(2021)

Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB2
Cancers 2021, 13, 982

Target Products / Applications

Epoxy beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Y. Kabe et al. (2021)

Glycyrrhizin derivatives suppress cancer chemoresistance by inhibiting progesterone receptor membrane component 1
Cancers, 13, 3265 (2021)

Target Products / Applications

NH₂ beads Chemical Biology Compounds Immobilization

PapersOthers（Reference ducuments）Limited proteolysis

Nakae et al.(2021) [nSMOL]

Potential application of measuring serum infliximab levels in rheumatoid arthritis management: A retrospective study based on KURAMA cohort data
PLoS ONE 16(10): e0258601

PapersOthers（Reference ducuments）Using the antibody-immobilized beads/Immunoprecipitation

S. Kageyama et al. (2021)

Identification of the mutation signature of the cancer genome caused by irradiation
Radiotherapy and Oncology 155 (2021) 10

Target Products / Applications

Protein A beads Protein G beads HM beads (FG beads HM) Immunoprecipitation Antibodies Immobilization

PapersReference ducuments using the beads that protein was immobilized

Suzuki et al.(2021)

A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling
eLife 2021;10:e69883.

Target Products / Applications

NHS beads Immunoprecipitation Compounds Immobilization

PapersReference ducuments using the beads that protein was immobilized

Kaneko et al.(2021)

Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential
Cancers 2021, 13, 2126

Target Products / Applications

Protein A beads Protein G beads HM beads (FG beads HM) Immunoprecipitation Antibodies Immobilization

PapersOthers（Reference ducuments）

Miyachi et al.(2021)

Serum Anti-oligodendrocyte Autoantibodies in Patients With Multiple Sclerosis Detected by a Tissue-Based Immunofluorescence Assay
Front Neurol. 2021 Aug 5;12:681980

PapersOthers（Reference ducuments）Limited proteolysis

M. Ohuchi et al. (2021) [nSMOL]

Use of an alternative signature peptide during development of a LC-MS/MS assay of plasma nivolumab levels applicable for multiple species
Journal of Chromatography B 1162 (2021) 122489

Target Products / Applications

NHS beads

PapersOthers（Reference ducuments）Exosome

Zhang X et al. (2021) [ExoCounter]

BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells
Oncogene 1516 (2021) 40

Target Products / Applications

NHS beads Virus / Exosome Isolation Antibodies Immobilization

PapersOthers（Reference ducuments）

Nomura et al.(2021)

Stimulation of the Runx2 P1 promoter by collagen-derived dipeptide prolyl-hydroxyproline bound to Foxg1 and Foxo1 in osteoblasts
Bioscience Reports (2021) 41 BSR20210304

Target Products / Applications

NHS beads

PapersOthers（Reference ducuments）Limited proteolysis

Koguchi et al.(2021) [nSMOL]

Trough levels of ipilimumab in serum as a potential biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab
J Immunother Cancer 2021;9:e002663

PapersReference ducuments using the beads that DNA was immobilized

Ozawa et al.(2021)

Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology
Cell Chemical Biology 28, July 15, 2021

Target Products / Applications

Protein A beads Protein G beads HM beads (FG beads HM) Immunoprecipitation Antibodies Immobilization

Papers

Chang Ni et al.(2021)

An Ultrasensitive Virus ELISA Based on a magnetic Mesoporous Silica Nanoprobe
Particle Volume38, Issue11 November 2021, 2100146

PapersOthers（Reference ducuments）Limited proteolysis

Brendan D Curti et al.(2021) [nSMOL]

Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor
J Immunother Cancer 2021;9:e002371

PapersOthers（Reference ducuments）Phage display

K. Fukunaga et al. (2021)

Directed evolution of orthogonal RNA–RBP pairs through library-vs-library in vitro selection
Nucleic Acids Research, gkab527 (2021)

Target Products / Applications

Streptavidin beads NeutrAvidin beads HM beads (FG beads HM) Phage Display DNA

PapersReference ducuments using the beads that compound was immobilized

Nan Yagishita-Kyo et al. (2021)

Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus
Biochemical and Biophysical Research Communications 551 (2021) 54

Target Products / Applications

COOH beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

T. Tsukahara et al. (2021)

Adenine nucleotide translocase 2, a putative target protein for 2-carba cyclic phosphatidic acid in microglial cells
Cellular Signalling 82 (2021) 109951

Target Products / Applications

Alkyne beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

Saito et al.(2021)

α-Trifluoromethyl Chalcones as Potent Anticancer Agents for Androgen Receptor-Independent Prostate Cancer
Molecules 2021, 26, 2812

Target Products / Applications

Azide beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that DNA was immobilized

Kinoshita et al.(2021)

Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells
Development (2021) 148 (16): dev188755

Target Products / Applications

Plain beads Analysis of DNA / RNA Binding Substances DNA

Reference ducuments using the beads that protein was immobilized

Takahashi et al.(2020)

A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors
Biomedicines 2020, 8, 152

Target Products / Applications

NHS beads Immunoprecipitation Antibodies Immobilization

Papers

Yoshioka et al.(2020)

4-Hydroxyderricin and xanthoangelol isolated from Angelica keiskei prevent dexamethasone-induced muscle loss
Food Funct., 2020, 11, 5498-5512

PapersReference ducuments using the beads that protein was immobilized

Kang et al.(2020)

Comprehensive analysis on the whole Rho-GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9
The FASEB Journal. 2020;34:8326-8340

Target Products / Applications

Immunoprecipitation Antibodies Immobilization

PapersReference ducuments using the beads that compound was immobilized

Takano et al.(2020)

The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach
Int J Mol Sci. 2020 Feb 20;21(4):1451

Target Products / Applications

NHS beads Chemical Biology Compounds Immobilization

Papers

Tsushima et al.(2020)

Target Protein Identification on Photocatalyst-Functionalized Magnetic Affinity Beads
Currentprotocols, https://doi.org/10.1002/cpps.108

PapersReference ducuments using the beads that compound was immobilized

Asatsuma-Okumura et al.(2020)

Molecular Mechanisms of the Teratogenic Effects of Thalidomide
Pharmaceuticals 2020, 13, 95; doi:10.3390/ph13050095

Target Products / Applications

NH₂ beads Chemical Biology Compounds Immobilization

PapersReference ducuments using the beads that compound was immobilized

K. Fujita et al. (2020)

Pesticide treatment reduces hydrophobic pollutant contamination in Cucurbita pepo through competitive binding to major latex-like proteins
Environmental Pollution 266 (2020) 115179

Target Products / Applications

Epoxy beads Chemical Biology Compounds Immobilization