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Kawatani et al.(2014)
Affinity-based target identification for bioactive small molecules
Med. Chem. Commun., 2014,5, 277-287
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M. Oda et al. (2014)
Vizantin Inhibits Endotoxin-Mediated Immune Responses via the TLR 4/MD-2 Complex
J. Immunol., 193, 4507 (2014).
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Westermaier et al.(2014)
Virtual screening: An in silico tool for interlacing the chemical universe with the proteome
Methods Volume 71, 1 January 2015, Pages 44-57
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T. Hosoi et al. (2014)
Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
EMBO Molecular Medicine, DOI: 10.1002 (2014).
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Sato et al.(2014)
Affinity-Based Isolation of Molecular Targets of Clinically Used Drugs
Concepts and Case Studies in Chemical Biology Chapter 15
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Kuno et al.(2014)
Differential Glycan Analysis of an Endogenous Glycoprotein: Toward Clinical Implementation—From Sample Pretreatment to Data Standardization
Methods in Molecular Biology book series (MIMB,volume 1200) Lectins pp 265–285
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P. P. Chamberlain et al. (2014)
Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat. Struct. Mol. Biol., 21, 803 (2014).
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A. Perez-Perarnau et al. (2014)
A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins
Angew. Chem. Int. Ed., 53, 10150 (2014).
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Chang et al.(2014)
Mechanism of immunomodulatory drugs’ action in the treatment of multiple myeloma
Acta Biochimica et Biophysica Sinica, Volume 46, Issue 3, March 2014, Pages 240–253
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S. Sakamoto et al. (2014)
Magnetically Promoted Rapid Immunoreactions Using Functionalized Fluorescent Magnetic Beads:A Proof of Principle
Clinical Chemistry, 60:4 (2014).
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K. Kai et al. (2014)
An acyl-SAM analog as an affinity ligand for identifying quorum sensing signal synthases
Chem. Commun., DOI:10.1039 (2014).
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V. Gupta et al. (2014)
Affinity Chromatographic Materials.
Encyclopedia of Polymeric Nanomaterials, DOI:10.1007 (2014).
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Enpuku et al.(2014)
Liquid-phase immunoassay utilizing binding reactions between magnetic markers and targets in the presence of a magnetic field
Applied Physics Express, Volume 7, Number 9 (2014) 097001
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Uchida et al.(2014)
Highly Sensitive Liquid-Phase Detection of Biological Targets With Magnetic Markers and High Tc SQUID
IEEE Transactions on Applied Superconductivity Volume: 24, Issue: 4, August 2014
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N. Iwamoto et al. (2014) [nSMOL]
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K. Takahashi et al. (2014)
Functional Analysis of Light-harvesting-like Protein 3 (LIL3) and Its Lightharvesting Chlorophyll-binding Motif in Arabidopsis
J. Biol. Chem., 289, 987 (2014).
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Y. Tokunaga et al. (2014)
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Ueda et al.(2014)
Performance of Filters in Medical Protein Separation System Using Superconducting Magnet
IEEE Transactions on Applied Superconductivity (Volume: 24, Issue: 3, June 2014)
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Uchida et al.(2013)
Liquid-phase detection of biological targets with magnetic markers and high Tc SQUID
2013 IEEE 14th International Superconductive Electronics Conference (ISEC) DOI: 10.1109/ISEC.2013.6604304
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Wustrow et al.(2013)
Inhibition of Ubiquitin Proteasome System Enzymes for Anticancer Therapy
Annual Reports in Medicinal Chemistry Volume 48, 2013, Pages 205-225
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M. Oishi et al. (2013)
Apigenin sensitizes prostate cancer cells to Apo2L/TRAIL by targeting adenine nucleotide translocase-2
PLOS ONE, 8, e55922 (2013).
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Umeda et al.(2013)
PGJIFs, new mitochondrial PGJ2 target factors, regulate cell proliferation
Journal of Biosciences and Medicines, 2013, 1, 11-15
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H. Inui et al. (2013)
A major latex-like protein is a key factor in crop contamination by persistent organic pollutants
Plant Physiology, 161, 2128 (2013).
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Futamura et al.(2013)
Target identification of small molecules based on chemical biology approaches
Mol. BioSyst., 2013,9, 897-914
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Tsujita et al.(2013) [ExoCounter]
Ultrahigh-Sensitivity Biomarker Sensing System Based on the Combination of Optical Disc Technologies and Nanobead Technologies
Japanese Journal of Applied Physics 52 (2013) 09LB02
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K. Hotta et al. (2013)
Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein
Mol. Pharmacol., 83, 930 (2013).
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Uebi et al.(2013)
Prohibitins, novel vitamin K2 target factors in osteoblast
Journal of Biosciences and Medicines, 2013, 1, 1-4
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Y. Iizumi et al. (2013)
The Flavonoid Apigenin Downregulates CDK1 by DirectlyTargeting Ribosomal Protein S9
PLOS ONE, 8, e73219 (2013).
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S. Karasawa et al. (2013)
Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis
Mol. Pharmacol., 83, 613 (2013).
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Umeda et al.(2013)
Effective cofactor complex purification using nanobeads
Journal of Biosciences and Medicines, 2013, 1, 5-10
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M.Arita. (2013)
Development of poliovirus extraction method from the stool extracts by using magnetic nanoparticles sensitized with soluble poliovirus receptor.
J. Clin. Microbiol. DOI:10.1128 (2013).
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M. Oda et al. (2013)
DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation
PLOS Genetics, 9, e1003574 (2013).
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A. Ikeda-Boku et al. (2013)
Protein fishing using magnetic nano-beads containing calmodulin site-specifically immobilized via an azido-group
J. Biochem., DOI:10.1093 (2013).
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V. Gupta et al. (2013)
Salicylic Acid Induces Mitochondrial Injury by Inhibiting Ferrochelatase Heme Biosynthesis Activity
Mol. Pharmacol., DOI:10.1124 (2013).
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Y. Ito et al. (2012)
Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol A
PLOS ONE, 7, e50481 (2012).
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A Lopez-Girona et al.(2012)
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
Leukemia volume 26, pages2326–2335 (2012)
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T. Ito, H. Handa. (2012)
Deciphering the mystery of thalidomide teratogenicity
Congenital Anomalies, 52, 1 (2012)
- 論文その他の論文ケミカルバイオロジー総論
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M. Ueda. (2012)
Chemical Biology of Natural Products on the Basis of Identification of Target Proteins.
Chem. Lett., 41, 658 (2012).
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M. Golan-Mashiach et al. (2012)
Identification of CTCF as a master regulator of the clustered protocadherin genes
Nucl. Acids Res., 40, 3378 (2012).
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J. Liu et al. (2012)
Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms
Scientific Reports, 2, 905 (2012).
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E. Okuda-Ashitaka et al. (2012)
Identification of NIPSNAP1 as a Nocistatin-interacting Protein Involving Pain Transmission
J. Biol. Chem., 287, 10403 (2012).
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S. Sakamoto et al. (2012)
Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound.
Bioorg. Med. Chem., 20, 1990 (2012).
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Tashiro et al.(2012)
Target identification of bioactive compounds
Bioorganic & Medicinal Chemistry Volume 20, Issue 6, 15 March 2012, Pages 1910-1921
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N. Maekawa et al. (2011)
High-performance affinity purification for identification of 15-deoxy-D12,14-PGJ2 interacting factors using magnetic nanobeads
Biomed. Chromatogr., 25, 466 (2011).
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T. Ito, H. Ando, H. Handa. (2011)
Teratogenic effects of thalidomide:molecular mechanisms
Cell. Mol. Life Sci., 68,1569 (2011).
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T. Ito et al. (2010)
Identification of a Primary Target of Thalidomide Teratogenicity
Science, 327, 1345 (2010).
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K. Kume et al. (2010)
Role of N-end rule ubiquitin ligases UBR1 and UBR2 inregulating the leucine-mTOR signaling pathway
Genes Cells, 15, 339 (2010).
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A. Sandhu et al. (2010)
Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics
Nanotechnology, 21, 442001 (2010).