Chemical Biology
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H. Tsugawa et al. (2020)
- PapersReference ducuments using the beads that compound was immobilized
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J. Cho et al. (2020)
L-Arginine prevents cereblon-mediated ubiquitination of glucokinase and stimulates glucose-6-phosphate production in pancreatic β-cells
Communications Biology (2020) 3:497
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T. Ito et al. (2020)
Molecular mechanisms of thalidomide and its derivatives
Proc. Jpn. Acad., Ser. B 96 (2020)
- PapersReference ducuments using the beads that compound was immobilized
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Y. Kabe et al. (2020)
Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites
npj Science of Food (2020) 4
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J. Cho et al. (2020)
UGGT1 retains proinsulin in the endoplasmic reticulum in an arginine dependent manner
Biochemical and Biophysical Research Communications 527 (2020) 668
- PapersReference ducuments using the beads that compound was immobilized
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T. Furukawa et al (2020)
Dioctatin Activates ClpP to Degrade Mitochondrial Components and Inhibits Aflatoxin Production
Cell Chemical Biology 27 (2020) 1396
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Wu et al.(2019)
Anti-Inflammatory and Anticancer Properties of Bioactive Compounds from Sesamum indicum L.—A Review
Molecules 2019, 24, 4426
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Kurata et al.(2019)
Food-Derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites
iScience 22, 336–352, December 20, 2019
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Yamada et al.(2019)
Effect of fatty acids on melanogenesis and tumor cell growth in melanoma cells
Journal of Lipid Research Volume 60, (2019) 1491
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Raymond Wu et al.(2019)
Baicalein targets GTPase-mediated autophagy to eliminate liver tumor initiating stem cell-like cells resistant to mTORC1 inhibition
Hepatology. 2018 November ; 68(5): 1726–1740
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J. Goto et al. (2019)
Uptake mechanisms of polychlorinated biphenyls in Cucurbita pepo via xylem sap containing major latex-like proteins
Environ. Exp. Bot., 162, 399(2019)
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Y. Yoshioka et al. (2019)
Glabridin inhibits dexamethasone-induced muscle atrophy
Arch. Biochem. Biophys., 664, 157(2019)
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T. Asatsuma-Okumura el al. (2019)
Molecular mechanisms of cereblon-based drugs
Pharmacology & Therapeutics, 202, 132(2019)
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M. Tera el al. (2019)
Identification of a binding protein for sesamin and characterization of its roles in plant growth
Scientific Reports, 9, 8631(2019)
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H. Tan et al. (2019)
Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5
J. Agric. Food Chem., 67, 3333(2019)
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Y. Uchihara et al. (2019)
Methotrexate significantly induces apoptosis by inhibiting STAT3 activation in NPM-ALK-positive ALCL cells
Biochemical Pharmacology, 170 (2019) 113666
- PapersReference ducuments using the beads that compound was immobilized
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Li et al.(2018)
IMiD compounds affect CD34+ cell fate and maturation via CRBN-induced IKZF1 degradation
Blood Adv (2018) 2 (5): 492–504
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Ito et al.(2018)
Development of a new affinity nanobead technology and target isolation of bioactive compounds
IOP Publishing Ltd 2018, Magnetic Nanoparticles for Medical Diagnostics Pages 3-1 to 3-27
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Yoshimura et al.(2018)
Morin suppresses cachexia-induced muscle wasting by binding to ribosomal protein S10 in carcinoma cells
Biochemical and Biophysical Research Communications 506 (2018) 773-779
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Patel et al.(2018)
Synthetic microbial ecology and nanotechnology for the production of Taxol and its precursors: A step towards sustainable production of cancer therapeutics
Design of Nanostructures for Theranostics Applications.
DOI: http://dx.doi.org/10.1016/B978-0-12-813669-0.00014-2
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Kabe et al.(2018)
Function and structural regulation of the carbon monoxide (CO) responsive membrane protein PGRMC1
J. Clin. Biochem. Nutr. 63 (2018) 12–17
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Y. Aono et al. (2018)
Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2
Biochem. Biophys. Res. Commun., 505, 1203 (2018).
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T. mori et al. (2018)
Structural basis of thalidomide enantiomer binding to cereblon
Scientific Reports, 8, 1294 (2018).
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Keane K.Y. Lai et al.(2017)
Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via Wnt Signaling and Stabilization of Low Density Lipoprotein Receptor-related Proteins 5 and 6
Gastroenterology. 2017 May ; 152(6): 1477–1491
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H. Ono et al. (2017)
Ribosomal protein S3 regulates XIAP expression independently of the NF-κB pathway in breast cancer cells
ONCOLOGY REPORTS, 38, 3205 (2017).
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Fuchs et al.(2017)
Immunomodulatory drugs and their therapeutic effect in hematological malignancies through cereblon
Hematol Med Oncol, 2017 Volume 2(3): 1-8
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M. Watanabe et al. (2017)
The pleiotropic regulation of cyclin D1 by newly identified sesaminol-binding protein ANT2
Oncogenesis, 6, e311 (2017).
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M. Boccitto et al. (2017)
The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK
Mar. Drugs, 15, 246 (2017).
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M. Tsushima et al. (2017)
Selective purification and chemical labeling of a target protein on ruthenium photocatalystfunctionalized affinity beads
Chem. Commun., 53, 4838 (2017).
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Nugyen et al.(2016)
Glutamine triggers acetylation-dependent degradation of glutamine synthetase via the thalidomide receptor cereblon
Mol Cell. 2016 March 17; 61(6): 809–820
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Tashiro et al.(2016)
Screening and target identification of bioactive compounds that modulate cell migration and autophagy
Bioorganic & Medicinal Chemistry Volume 24, Issue 15, 1 August 2016, Pages 3283-3290
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T. Taniguchi et al. (2016)
Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer
Cell Death Dis., 7, e2211 (2016).
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Y. kabe et al. (2016)
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nature Communications, 7:11030 (2016).
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Nariai et al.(2015)
Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase C (PKC ) Interaction by (-)-Maackiain Suppresses Histamine H1 Receptor Gene Transcription in HeLa Cells
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 45, pp. 27393
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Kampmann et al.(2015)
The synthesis and fluorescence profile of novel thalidomide analogues
Tetrahedron Volume 71, Issue 42, 21 October 2015, Pages 8140-8149
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Sun et al.(2015)
Hunting Molecular Targets for Anticancer Reagents by Chemical Proteomics
Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 2015, Pages 347-363
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T. Furukawa et al. (2015)
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K. Ishii, Y.Sugimura. (2015)
Identification of a new pharmacological activity of the phenylpiperazine derivative naftopidil:tubulin-binding drug
J. Chem. Biol., 8, 5 (2015).
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Y. Soeda et al. (2015)
Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups
Nature Communications, 6:10216 (2015).
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Jung et al.(2015)
Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery
Archives of Pharmacal Research volume 38, pages1627–1641 (2015)
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Van den Broeck et al.(2015)
Drug Targets, Target Identification, Validation, and Screening
The Practice of Medicinal Chemistry (Fourth Edition) 2015, Pages 45-70
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T. Suzuki et al. (2015)
Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage
J. Am. Soc. Nephrol., DOI:10.1681 (2015).
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Sato et al.(2014)
Affinity-Based Isolation of Molecular Targets of Clinically Used Drugs
Concepts and Case Studies in Chemical Biology Chapter 15
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Kawatani et al.(2014)
Affinity-based target identification for bioactive small molecules
Med. Chem. Commun., 2014,5, 277-287
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T. Hosoi et al. (2014)
Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
EMBO Molecular Medicine, DOI: 10.1002 (2014).
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P. P. Chamberlain et al. (2014)
Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat. Struct. Mol. Biol., 21, 803 (2014).
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Chang et al.(2014)
Mechanism of immunomodulatory drugs’ action in the treatment of multiple myeloma
Acta Biochimica et Biophysica Sinica, Volume 46, Issue 3, March 2014, Pages 240–253
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Westermaier et al.(2014)
Virtual screening: An in silico tool for interlacing the chemical universe with the proteome
Methods Volume 71, 1 January 2015, Pages 44-57
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A. Perez-Perarnau et al. (2014)
A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins
Angew. Chem. Int. Ed., 53, 10150 (2014).
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K. Kai et al. (2014)
An acyl-SAM analog as an affinity ligand for identifying quorum sensing signal synthases
Chem. Commun., DOI:10.1039 (2014).
